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α-Arbutin is similar to β-Arbutin, which can inhibit the production and deposition of melanin, and remove pigmentation and freckles. Studies have shown that α-arbutin can inhibit the activity of tyrosinase at a relatively low concentration, and its inhibitory effect on tyrosinase is better than that of β-arbutin. Alpha-arbutin can be used in cosmetics as a whitening agent, such as Zihuating.

α-Arbutin is a new type of whitening raw material. α-Arbutin can be quickly absorbed by the skin and selectively inhibit the activity of tyrosinase, thereby blocking the synthesis of melanin, but it does not affect the normal growth of epidermal cells, nor does it inhibit the expression of tyrosinase itself. At the same time, α-arbutin can also promote the decomposition and excretion of melanin, so as to avoid the deposition of skin pigment and eliminate pigmentation and freckles. The action process of α-arbutin does not produce hydroquinone, nor does it produce side effects such as toxicity and irritation to the skin and allergies. The above characteristics determine that α-arbutin can be used as the safest and most effective raw material for skin whitening and discoloration so far. α-Arbutin has the functions of disinfecting and moisturizing the skin, anti-allergic, and can also help the healing of damaged skin. These properties allow α-arbutin to be widely used in cosmetics.